Latest Papers

Where inside a tumor do dendritic cells, the command centers of immunity, gather, and who are their neighbors? This article explains a preprint, not yet peer reviewed, that brings together single-cell analysis of 28 human and 12 mouse datasets, spatial transcriptomics of human colorectal cancer, and multiplexed imaging of more than 1.4 million cells in mouse melanoma. After immunotherapy, the detectable changes in the transcriptional states of dendritic cells were minimal, whereas their spatial arrangement clearly changed.

Neuroscience evolves daily, with new techniques emerging to unravel the brain's mysteries. Here we introduce an innovative study on the mouse prefrontal cortex and explain its findings.

Alzheimer's disease is a serious challenge affecting many lives. However, recent research is opening new therapeutic avenues. This article explains the latest study on the VCAM1–ApoE pathway.

A new spatial single-cell mass spectrometry approach characterizes the zonation of the hepatocyte proteome. This article explains the study's main findings and its applications.

Using a high-throughput proteomics platform measuring thousands of plasma proteins, this study combined genetic and phenotypic data to explore bridging the gap between genome and disease.

The paper introduced today is the following. First, Salvador, A.F.M., et al., 2023. Age-dependent immune and lymphatic responses after spinal cord injury. Neuron.

The paper introduced this time is here. Microglial-to-neuronal CCR5 signaling regulates autophagy in neurodegeneration B. P. Festa, F.

A very interesting paper has been published in Nature. In short, the motor homunculus brain map is not as simple as reality; the cortex also coordinates with other important networks.