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Clinical

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Clinical
2026-08-01

Antibody ALMB-0166 Calms Overactive Astrocytes — Safety and Early Signals from a First-in-Human Trial in Spinal Cord Injury

ALMB-0166, the first Cx43-hemichannel antibody, given as a single dose to 24 SCI patients: adverse events matched placebo, 1200/2400mg improved scores, two reached AIS E. A small, exploratory result.
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Clinical
2026-08-01

Knee Joint Injections: Which One Actually Works?—From Steroids to Exosomes, Decoding 9 Treatments at the Molecular Level

A narrative review of knee injections, corticosteroids to exosomes: an RCT tying repeated triamcinolone to cartilage loss, and the evidence-maturity gap across PRP, orthobiologics, MSCs, exosomes.
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Clinical
2026-07-27

Can the Brain Reclaim a Bladder That Won’t Move After Spinal Cord Injury? — What the Anti-RGMa Antibody Elezanumab Showed in Rats

Neurogenic bladder afflicts more than 80% of people with spinal cord injury. A careful reading of a preclinical study reporting that the anti-RGMa antibody elezanumab improved voiding function and neuroplasticity in rats. Efficacy in humans has not yet been shown.
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Clinical
2023-10-30

TAVR (Transcatheter Aortic Valve Replacement): An Innovative Advance in Heart Disease Treatment

Hello, and welcome to everyone interested in the latest advances in heart disease treatment! Today we focus on an innovative surgical technique called TAVR (Transcatheter Aortic Valve Replacement).
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Clinical
2023-10-27

What Is ATTR Cardiac Amyloidosis? A Thorough Explanation of the Efficacy and Safety of the Latest Treatment, Patisiran — From the Results of the NEJM APOLLO-B Trial

Heart health greatly affects our quality of life, but a progressive disease called ATTR cardiac amyloidosis threatens it. This article explains the basics of ATTR amyloidosis and focuses on Patisiran.
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Clinical
2023-04-25

A new treatment for hemophilia: from the Lancet

The paper introduced here is the following. Efficacy and safety of fitusiran prophylaxis in people with haemophilia A or haemophilia B with
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